Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0007596 | biological_process | blood coagulation |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE R11 B 1 |
| Chain | Residue |
| B | HIS57 |
| B | SER195 |
| B | SER214 |
| B | TRP215 |
| B | GLY216 |
| B | GLY219 |
| B | GLY226 |
| B | TYR60 |
| B | TRP60 |
| B | GLU97 |
| B | ASN98 |
| B | LEU99 |
| B | ILE174 |
| B | ASP189 |
| B | ALA190 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR CHAIN C OF HIRUDIN IIB |
| Chain | Residue |
| B | PHE34 |
| B | GLN38 |
| B | LEU40 |
| B | LEU65 |
| B | ARG73 |
| B | THR74 |
| B | ARG75 |
| B | ARG75 |
| B | TYR76 |
| B | LYS81 |
| B | ILE82 |
| B | MET84 |
| B | HOH543 |
| B | HOH703 |
| B | HOH792 |
| C | HOH582 |
| C | HOH630 |
| C | HOH647 |
| C | HOH650 |
| C | HOH671 |
| C | HOH675 |
| C | HOH687 |
| C | HOH713 |
| C | HOH736 |
| C | HOH754 |
| C | HOH779 |
| C | HOH784 |
| C | HOH803 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
| Chain | Residue | Details |
| B | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Sulfotyrosine => ECO:0000250 |
| Chain | Residue | Details |
| C | TYS263 | |
| B | ASP102 | |
| B | SER195 | |
| Chain | Residue | Details |
| B | ASN60 | |
