1G2W

E177S MUTANT OF THE PYRIDOXAL-5'-PHOSPHATE ENZYME D-AMINO ACID AMINOTRANSFERASE

Summary for 1G2W

• Entry DOI: 10.2210/pdb1g2w/pdb
• Related: 1A0G 1DAA 2DAA 2DAB 3DAA 4DAA 5DAA
• Descriptor: D-ALANINE AMINOTRANSFERASE, ACETATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total)
• Functional Keywords: mutant, pyridoxal-5'-phosphate, water molecule, internal aldimine, aminotransferase, bacterial cell wall biosynthesis, transferase
• Biological source: Geobacillus stearothermophilus
• Total number of polymer chains: 2
• Total formula weight: 65152.12

Authors

Lepore, B.W.,Ringe, D. (deposition date: 2000-10-21, release date: 2000-11-15, Last modification date: 2021-11-03)

• Primary citation: van Ophem, P.W.,Lepore, B.W.,Kishimoto, K.,Ringe, D.,Manning, J.M.; Studies on an Active Site Residue, E177, That Affects Binding of the Coenzyme in D-Amino Acid Transaminase, and Mechanistic Studies on a Suicide Substrate; Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins, 10th Annual International Symposium on Vitamin B6, :339-346, 2000

Experimental method

X-RAY DIFFRACTION (2 Å)