1G2K
HIV-1 PROTEASE WITH CYCLIC SULFAMIDE INHIBITOR, AHA047
Summary for 1G2K
Entry DOI | 10.2210/pdb1g2k/pdb |
Related | 1ajv 1ajx |
Descriptor | PROTEASE RETROPEPSIN, 3-(7-BENZYL-4,5-DIHYDROXY-1,1-DIOXO-3,6-BIS-PHENOXYMETHYL-1L6-[1,2,7]THIADIAZEPAN-2-YLMETHYL)-N-METHYL-BENZAMIDE (3 entities in total) |
Functional Keywords | hiv, protease inhibitors, hydrolase |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04587 |
Total number of polymer chains | 2 |
Total formula weight | 22239.25 |
Authors | Lindberg, J.,Unge, T. (deposition date: 2000-10-20, release date: 2001-06-01, Last modification date: 2023-08-09) |
Primary citation | Schaal, W.,Karlsson, A.,Ahlsen, G.,Lindberg, J.,Andersson, H.O.,Danielson, U.H.,Classon, B.,Unge, T.,Samuelsson, B.,Hulten, J.,Hallberg, A.,Karlen, A. Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors. J.Med.Chem., 44:155-169, 2001 Cited by PubMed: 11170625DOI: 10.1021/jm001024j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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