1FVE
X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING
Summary for 1FVE
Entry DOI | 10.2210/pdb1fve/pdb |
Descriptor | IGG1-KAPPA 4D5 FAB (LIGHT CHAIN), IGG1-KAPPA 4D5 FAB (HEAVY CHAIN) (3 entities in total) |
Functional Keywords | immunoglobulin |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 94353.11 |
Authors | Eigenbrot, C.,Randal, M.,Presta, L.,Kossiakoff, A.A. (deposition date: 1992-10-20, release date: 1993-10-31, Last modification date: 2017-11-29) |
Primary citation | Eigenbrot, C.,Randal, M.,Presta, L.,Carter, P.,Kossiakoff, A.A. X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling. J.Mol.Biol., 229:969-995, 1993 Cited by PubMed: 8095303DOI: 10.1006/jmbi.1993.1099 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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