1FOE

CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1

1FOE の概要

• エントリーDOI: 10.2210/pdb1foe/pdb
• NMR情報: BMRB: 5511
• 分子名称: T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: dbl homology domain, pleckstrin homology domain, gtpase, guanine nucleotide exchange factor, signaling protein, immune system-signaling protein complex, immune system/signaling protein
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cell junction (By similarity): Q60610; Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P63000
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 254537.46

構造登録者

Worthylake, D.K.,Rossman, K.L.,Sondek, J. (登録日: 2000-08-27, 公開日: 2001-01-17, 最終更新日: 2011-07-13)

• 主引用文献: Worthylake, D.K.,Rossman, K.L.,Sondek, J.; Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.; Nature, 408:682-688, 2000; PubMed: 11130063; DOI: 10.1038/35047014

実験手法

X-RAY DIFFRACTION (2.8 Å)