1FK8

THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY

1FK8 の概要

• エントリーDOI: 10.2210/pdb1fk8/pdb
• 関連するPDBエントリー: 1FJH
• 分子名称: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: short chain dehydrogenase, sdr, carbonyl reductase, steroid, hydroxysteroid, xenobiotic, metyrapone, oligomerisation, comamonas testosteroni, nad, nicotinamide adenine dinucleotide, substrate binding loop, oxidoreductase
• 由来する生物種: Comamonas testosteroni
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54167.71

構造登録者

Grimm, C.,Ficner, R.,Maser, E.,Klebe, G.,Reuter, K. (登録日: 2000-08-09, 公開日: 2001-01-17, 最終更新日: 2024-02-07)

• 主引用文献: Grimm, C.,Maser, E.,Mobus, E.,Klebe, G.,Reuter, K.,Ficner, R.; The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family.; J.Biol.Chem., 275:41333-41339, 2000; PubMed: 11007791; DOI: 10.1074/jbc.M007559200

実験手法

X-RAY DIFFRACTION (1.95 Å)