Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0140169 | molecular_function | 3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0140169 | molecular_function | 3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD A 800 |
| Chain | Residue |
| A | GLY8 |
| A | CYS69 |
| A | ALA70 |
| A | GLY71 |
| A | LEU72 |
| A | VAL85 |
| A | ILE112 |
| A | SER113 |
| A | SER114 |
| A | TYR155 |
| A | LYS159 |
| A | ALA10 |
| A | PRO185 |
| A | GLY186 |
| A | THR188 |
| A | THR190 |
| A | HOH2109 |
| A | THR11 |
| A | GLY12 |
| A | ILE13 |
| A | ASP32 |
| A | ALA40 |
| A | ASP41 |
| A | LEU42 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAD B 1800 |
| Chain | Residue |
| B | GLY1008 |
| B | ALA1010 |
| B | THR1011 |
| B | GLY1012 |
| B | ILE1013 |
| B | ASP1032 |
| B | ALA1040 |
| B | ASP1041 |
| B | LEU1042 |
| B | CYS1069 |
| B | ALA1070 |
| B | GLY1071 |
| B | LEU1072 |
| B | VAL1085 |
| B | ILE1112 |
| B | SER1113 |
| B | SER1114 |
| B | TYR1155 |
| B | LYS1159 |
| B | PRO1185 |
| B | ALA1187 |
| B | HOH2137 |
| B | HOH2236 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11007791","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ybv |
| Chain | Residue | Details |
| A | TYR155 | |
| A | SER114 | |
| A | ASN86 | |
| A | LYS159 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ybv |
| Chain | Residue | Details |
| B | SER1114 | |
| B | LYS1159 | |
| B | TYR1155 | |
| B | ASN1086 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ybv |
| Chain | Residue | Details |
| A | ASN152 | |
| A | LYS159 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ybv |
| Chain | Residue | Details |
| B | ASN1152 | |
| B | LYS1159 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ybv |
| Chain | Residue | Details |
| A | TYR155 | |
| A | LYS159 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ybv |
| Chain | Residue | Details |
| B | LYS1159 | |
| B | TYR1155 | |
