1FE8

CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING

Summary for 1FE8

Related1ATZ 1AO3
DescriptorVON WILLEBRAND FACTOR, IMMUNOGLOBULIN IGG RU5, N-ACETYL-D-GLUCOSAMINE, ... (7 entities in total)
Functional Keywordscollagen binding, conformational changes, epitope, von willebrand factor a-type domain, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains9
Total molecular weight201648.36
Authors
Bouma, B.,Huizinga, E.G.,Schiphorst, M.E.,Sixma, J.J.,Kroon, J.,Gros, P. (deposition date: 2000-07-21, release date: 2001-04-04, Last modification date: 2011-07-13)
Primary citation
Romijn, R.A.,Bouma, B.,Wuyster, W.,Gros, P.,Kroon, J.,Sixma, J.J.,Huizinga, E.G.
Identification of the collagen-binding site of the von Willebrand factor A3-domain.
J.Biol.Chem., 276:9985-9991, 2001
PubMed: 11098050 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M006548200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.03 Å)
NMR Information
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.256160.5%2.9%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution