1FDU
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221L COMPLEXED WITH ESTRADIOL AND NADP+
Summary for 1FDU
Entry DOI | 10.2210/pdb1fdu/pdb |
Descriptor | 17-BETA-HYDROXYSTEROID DEHYDROGENASE, SULFATE ION, ESTRADIOL, ... (5 entities in total) |
Functional Keywords | dehydrogenase, 17-beta-hydroxysteroid, mutant, estradiol, nadp |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P14061 |
Total number of polymer chains | 4 |
Total formula weight | 144243.24 |
Authors | Mazza, C.,Breton, R.,Housset, D.,Fontecilla-Camps, J.-C. (deposition date: 1998-01-14, release date: 1998-05-27, Last modification date: 2024-05-22) |
Primary citation | Mazza, C.,Breton, R.,Housset, D.,Fontecilla-Camps, J.C. Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase. J.Biol.Chem., 273:8145-8152, 1998 Cited by PubMed: 9525918DOI: 10.1074/jbc.273.14.8145 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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