1FCX
ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394
Summary for 1FCX
| Entry DOI | 10.2210/pdb1fcx/pdb |
| Related | 1EXA 1EXX 1fcy 1fcz 1fd0 2LBD 3LBD |
| Descriptor | RETINOIC ACID RECEPTOR GAMMA-1, 6-[HYDROXY-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, ... (4 entities in total) |
| Functional Keywords | isotype selectivity, retinoid ligand complexes, drug design, antiparallel alpha-helical sandwich fold, structural proteomics in europe, spine, structural genomics, gene regulation |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 27434.18 |
| Authors | Klaholz, B.P.,Mitschler, A.,Moras, D.,Structural Proteomics in Europe (SPINE) (deposition date: 2000-07-19, release date: 2000-09-11, Last modification date: 2023-08-09) |
| Primary citation | Klaholz, B.P.,Mitschler, A.,Moras, D. Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J.Mol.Biol., 302:155-170, 2000 Cited by PubMed: 10964567DOI: 10.1006/jmbi.2000.4032 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
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