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1FCX

ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0048384biological_processretinoic acid receptor signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues12
DetailsBINDING SITE FOR RESIDUE 184 A 450
ChainResidue
APHE201
ALEU400
AILE412
AHOH548
APHE230
ACYS237
ALEU271
AMET272
AILE275
APHE288
ASER289
AGLY303

site_idAC2
Number of Residues16
DetailsBINDING SITE FOR RESIDUE LMU A 451
ChainResidue
ALYS236
ALYS240
AGLU243
ACYS267
AASP340
AGLN354
APRO377
ALEU380
AILE383
ATHR384
AARG387
AHOH560
AHOH605
AHOH645
AHOH675
AHOH719

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS401

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PDB entries from 2024-10-16

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