1FCX

ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394

1FCX の概要

• エントリーDOI: 10.2210/pdb1fcx/pdb
• 関連するPDBエントリー: 1EXA 1EXX 1fcy 1fcz 1fd0 2LBD 3LBD
• 分子名称: RETINOIC ACID RECEPTOR GAMMA-1, 6-[HYDROXY-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, ... (4 entities in total)
• 機能のキーワード: isotype selectivity, retinoid ligand complexes, drug design, antiparallel alpha-helical sandwich fold, structural proteomics in europe, spine, structural genomics, gene regulation
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27434.18

構造登録者

Klaholz, B.P.,Mitschler, A.,Moras, D.,Structural Proteomics in Europe (SPINE) (登録日: 2000-07-19, 公開日: 2000-09-11, 最終更新日: 2023-08-09)

• 主引用文献: Klaholz, B.P.,Mitschler, A.,Moras, D.; Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.; J.Mol.Biol., 302:155-170, 2000; PubMed: 10964567; DOI: 10.1006/jmbi.2000.4032

実験手法

X-RAY DIFFRACTION (1.47 Å)