1F4D

CRYSTAL STRUCTURE OF E. COLI THYMIDYLATE SYNTHASE C146S, L143C COVALENTLY MODIFIED AT C143 WITH N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL

Summary for 1F4D

Entry DOI	10.2210/pdb1f4d/pdb
Related	1F4B 1F4C 1F4E 1F4F 1F4G
Descriptor	THYMIDYLATE SYNTHASE, SULFATE ION, N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL, ... (5 entities in total)
Functional Keywords	crystal structure of e. coli thymidylate synthase c146s, l143c covalently modified at c143 with n-[tosyl-d-prolinyl]amino-ethanethiol, transferase
Biological source	Escherichia coli
Cellular location	Cytoplasm : P0A884
Total number of polymer chains	2
Total formula weight	62292.51
Authors	Erlanson, D.A.,Braisted, A.C.,Raphael, D.R.,Randal, M.,Stroud, R.M.,Gordon, E.,Wells, J.A. (deposition date: 2000-06-07, release date: 2000-06-22, Last modification date: 2021-11-03)
Primary citation	Erlanson, D.A.,Braisted, A.C.,Raphael, D.R.,Randal, M.,Stroud, R.M.,Gordon, E.M.,Wells, J.A. Site-directed ligand discovery. Proc.Natl.Acad.Sci.USA, 97:9367-9372, 2000 Cited by PubMed: 10944209 DOI: 10.1073/pnas.97.17.9367 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation