1EZJ

CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS

Summary for 1EZJ

Entry DOI	10.2210/pdb1ezj/pdb
Descriptor	NUCLEOCAPSID PHOSPHOPROTEIN, ETHYL MERCURY ION, CALCIUM ION, ... (4 entities in total)
Functional Keywords	four stranded coiled coil, viral polymerase, sendai virus, tetramer, viral protein, transferase
Biological source	Sendai virus (strain Harris)
Cellular location	Host cytoplasm: P04859
Total number of polymer chains	1
Total formula weight	13385.54
Authors	Tarbouriech, N.,Curran, J.,Ruigrok, R.W.H.,Burmeister, W.P. (deposition date: 2000-05-11, release date: 2000-09-20, Last modification date: 2024-02-07)
Primary citation	Tarbouriech, N.,Curran, J.,Ruigrok, R.W.,Burmeister, W.P. Tetrameric coiled coil domain of Sendai virus phosphoprotein. Nat.Struct.Biol., 7:777-781, 2000 Cited by PubMed Abstract: The high resolution X-ray structure of the Sendai virus oligomerization domain reveals a homotetrameric coiled coil structure with many details that are different from classic coiled coils with canonical hydrophobic heptad repeats. Alternatives to the classic knobs-into-holes packing lead to differences in supercoil pitch and diameter that allow water molecules inside the core. This open and more hydrophilic structure does not seem to be destabilized by mutations that would be expected to disrupt classic coiled coils. PubMed: 10966649 DOI: 10.1038/79013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation