1EGN

CELLOBIOHYDROLASE CEL7A (E223S, A224H, L225V, T226A, D262G) MUTANT

Summary for 1EGN

Entry DOI	10.2210/pdb1egn/pdb
Related	1DY4 1EK7 1I5M 4CEL 7CEL
Descriptor	1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE CEL7A, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... (4 entities in total)
Functional Keywords	hydrolase, glycosidase, cellulase, cellulose degradation, glycoprotein, glycosylated protein, ph-mutant
Biological source	Hypocrea jecorina
Total number of polymer chains	1
Total formula weight	46330.75
Authors	Stahlberg, J.,Harris, M.,Jones, T.A. (deposition date: 2000-02-16, release date: 2001-05-16, Last modification date: 2021-11-03)
Primary citation	Becker, D.,Braet, C.,Brumer III, H.,Claeyssens, M.,Divne, C.,Fagerstrom, B.R.,Harris, M.,Jones, T.A.,Kleywegt, G.J.,Koivula, A.,Mahdi, S.,Piens, K.,Sinnott, M.L.,Stahlberg, J.,Teeri, T.T.,Underwood, M.,Wohlfahrt, G. Engineering of a glycosidase Family 7 cellobiohydrolase to more alkaline pH optimum: the pH behaviour of Trichoderma reesei Cel7A and its E223S/ A224H/L225V/T226A/D262G mutant. Biochem.J., 356:19-30, 2001 Cited by PubMed: 11336632 DOI: 10.1042/0264-6021:3560019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation