1E2H
The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography
Summary for 1E2H
Entry DOI | 10.2210/pdb1e2h/pdb |
Related | 1E2I 1E2J 1E2K 1E2L 1E2M 1E2N 1E2P 1KI2 1KI4 1KI5 1KI6 1KI7 1KI8 1KIM 1VTK 2VTK 3VTK |
Descriptor | THYMIDINE KINASE, SULFATE ION (3 entities in total) |
Functional Keywords | transferase, adenine analog, enzyme-prodrug gene therapy, nucleoside- binding, thymidine kinase |
Biological source | HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) |
Total number of polymer chains | 2 |
Total formula weight | 71750.30 |
Authors | Vogt, J.,Scapozza, L.,Schulz, G.E. (deposition date: 2000-05-23, release date: 2000-11-06, Last modification date: 2023-12-06) |
Primary citation | Vogt, J.,Perozzo, R.,Pautsch, A.,Prota, A.,Schelling, P.,Pilger, B.,Folkers, G.,Scapozza, L.,Schulz, G.E. Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41:545-, 2000 Cited by PubMed: 11056041DOI: 10.1002/1097-0134(20001201)41:4<545::AID-PROT110>3.0.CO;2-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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