1DM4

SER195ALA MUTANT OF HUMAN THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A (7-16)

Summary for 1DM4

DescriptorPROTEIN (ALPHA THROMBIN:LIGHT CHAIN), PROTEIN (MUTANT ALPHA THROMBIN:HEAVY CHAIN), PROTEIN (FIBRINOPEPTIDE), ... (4 entities in total)
Functional Keywordsmutant thrombin, residual catalytic activity, fibrinopeptide a, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space P00734 P00734
Total number of polymer chains3
Total molecular weight34907.9
Authors
Krishnan, R.,Sadler, E.J.,Tulinsky, A. (deposition date: 1999-12-13, release date: 2000-01-19, Last modification date: 2018-03-14)
Primary citation
Krishnan, R.,Sadler, J.E.,Tulinsky, A.
Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity.
Acta Crystallogr.,Sect.D, 56:406-410, 2000
PubMed: 10739913 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444900001487
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers892.8%19.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution