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1DE8

HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA

Summary for 1DE8
Entry DOI10.2210/pdb1de8/pdb
Related1BIX
DescriptorDNA (5'-D(*GP*CP*TP*AP*CP*(3DR)P*GP*AP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE, ... (4 entities in total)
Functional Keywordsenzyme:dna complex, dna repair, abasic site, lyase-dna complex, lyase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion: P27695
Total number of polymer chains6
Total formula weight75595.74
Authors
Mol, C.D.,Izumi, T.,Mitra, S.,Tainer, J.A. (deposition date: 1999-11-13, release date: 2000-02-02, Last modification date: 2024-02-07)
Primary citationMol, C.D.,Izumi, T.,Mitra, S.,Tainer, J.A.
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected
Nature, 403:451-456, 2000
Cited by
PubMed: 10667800
DOI: 10.1038/35000249
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

217705

건을2024-03-27부터공개중

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