1BIX

THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES

Summary for 1BIX

Entry DOI	10.2210/pdb1bix/pdb
Descriptor	AP ENDONUCLEASE 1, SAMARIUM (III) ION, PLATINUM (II) ION, ... (4 entities in total)
Functional Keywords	dna repair, endonuclease, hap1, ref-1, abasic site recognition
Biological source	Homo sapiens (human)
Cellular location	Nucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion: P27695
Total number of polymer chains	1
Total formula weight	33084.20
Authors	Gorman, M.A.,Morera, S.,Rothwell, D.G.,De La Fortelle, E.,Mol, C.D.,Tainer, J.A.,Hickson, I.D.,Freemont, P.S. (deposition date: 1998-06-19, release date: 1999-06-22, Last modification date: 2024-02-07)
Primary citation	Gorman, M.A.,Morera, S.,Rothwell, D.G.,de La Fortelle, E.,Mol, C.D.,Tainer, J.A.,Hickson, I.D.,Freemont, P.S. The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J., 16:6548-6558, 1997 Cited by PubMed: 9351835 DOI: 10.1093/emboj/16.21.6548 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation