1D6M

CRYSTAL STRUCTURE OF E. COLI DNA TOPOISOMERASE III

1D6M の概要

• エントリーDOI: 10.2210/pdb1d6m/pdb
• 分子名称: DNA TOPOISOMERASE III (1 entity in total)
• 機能のキーワード: dna topoisomerase, decatenating enzyme, isomerase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 73322.78

構造登録者

Mondragon, A.,DiGate, R. (登録日: 1999-10-14, 公開日: 2000-10-14, 最終更新日: 2024-02-07)

主引用文献

Mondragon, A.,DiGate, R.
The structure of Escherichia coli DNA topoisomerase III.
Structure Fold.Des., 7:1373-1383, 1999

PubMed Abstract: DNA topoisomerases are enzymes that change the topology of DNA. Type IA topoisomerases transiently cleave one DNA strand in order to pass another strand or strands through the break. In this manner, they can relax negatively supercoiled DNA and catenate and decatenate DNA molecules. Structural information on Escherichia coli DNA topoisomerase III is important for understanding the mechanism of this type of enzyme and for studying the mechanistic differences among different members of the same subfamily.

PubMed: 10574789
DOI: 10.1016/S0969-2126(00)80027-1

実験手法

X-RAY DIFFRACTION (3 Å)