1D4W
CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH SLAM PHOSPHOPEPTIDE
Summary for 1D4W
Entry DOI | 10.2210/pdb1d4w/pdb |
Related | 1D1Z 1D4T |
Descriptor | T CELL SIGNAL TRANSDUCTION MOLECULE SAP, SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE (3 entities in total) |
Functional Keywords | sh2 domain, phosphotyrosine recogniiton, peptide recognition, signal transduction, lymphoproliferative disease, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : O60880 Cell membrane ; Single-pass type I membrane protein. Isoform 3: Secreted . Isoform 4: Cell membrane : Q13291 |
Total number of polymer chains | 4 |
Total formula weight | 26125.77 |
Authors | Poy, F.,Yaffe, M.B.,Sayos, J.,Saxena, K.,Eck, M.J. (deposition date: 1999-10-06, release date: 1999-10-14, Last modification date: 2018-01-31) |
Primary citation | Poy, F.,Yaffe, M.B.,Sayos, J.,Saxena, K.,Morra, M.,Sumegi, J.,Cantley, L.C.,Terhorst, C.,Eck, M.J. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition. Mol.Cell, 4:555-561, 1999 Cited by PubMed: 10549287DOI: 10.1016/S1097-2765(00)80206-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report