1D1T

MUTANT OF HUMAN SIGMA ALCOHOL DEHYDROGENASE WITH LEUCINE AT POSITION 141

Summary for 1D1T

Related1AGN 1D1S
DescriptorALCOHOL DEHYDROGENASE CLASS IV SIGMA CHAIN, ZINC ION, ACETATE ION, ... (6 entities in total)
Functional Keywordsrossmann or dinucleotide fold, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P40394
Total number of polymer chains4
Total molecular weight164974.24
Authors
Xie, P.T.,Hurley, T.D. (deposition date: 1999-09-21, release date: 1999-09-29, Last modification date: 2018-04-04)
Primary citation
Xie, P.T.,Hurley, T.D.
Methionine-141 directly influences the binding of 4-methylpyrazole in human sigma sigma alcohol dehydrogenase.
Protein Sci., 8:2639-2644, 1999
PubMed: 10631979 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25691.1%2.0%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12