1D1T
MUTANT OF HUMAN SIGMA ALCOHOL DEHYDROGENASE WITH LEUCINE AT POSITION 141
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ALCOHOL DEHYDROGENASE CLASS IV SIGMA CHAIN | polymer | 373 | 39906.3 | 4 | UniProt (P40394) Pfam (PF08240) Pfam (PF00107) | Homo sapiens (human) | RETINOL DEHYDROGENASE, GASTRIC ALCOHOL DEHYDROGENASE |
| 2 | CA, DA, E, EA, F... (C, A, D, B) | ZINC ION | non-polymer | 65.4 | 19 | Chemie (ZN) | |||
| 3 | FA, GA, K, L, M... (C, A, D, B) | ACETATE ION | non-polymer | 59.0 | 13 | Chemie (ACT) | |||
| 4 | AA, O, X, Y, Z (B, A) | CACODYLATE ION | non-polymer | 137.0 | 5 | Chemie (CAC) | |||
| 5 | BA, HA, P, SA (B, C, A, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 6 | TA, UA, VA, WA (A, B, C, D) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 374 (UniProt: P40394)
| PDB | External Database | Details |
|---|---|---|
| Leu 141 | Met 141 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 159625.2 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 5349.0 | |
| All* | Total formula weight | 164974.2 |
