1CWS

HUMAN CDC25B CATALYTIC DOMAIN WITH TUNGSTATE

Summary for 1CWS

• Entry DOI: 10.2210/pdb1cws/pdb
• Related: 1CWR 1CWT 1QB0
• Descriptor: CDC25 B-TYPE TYROSINE PHOSPHATASE, TUNGSTATE(VI)ION, SULFATE ION, ... (6 entities in total)
• Functional Keywords: hydrolase, cell cycle phosphatase, dual specificity protein phosphatase, cdc25, cdc25b, cell cycle
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton, centrosome: P30305
• Total number of polymer chains: 1
• Total formula weight: 25364.95

Authors

Watenpaugh, K.D.,Reynolds, R.A.,Chidester, C.G. (deposition date: 1999-08-26, release date: 2000-08-30, Last modification date: 2011-07-13)

• Primary citation: Reynolds, R.A.,Yem, A.W.,Wolfe, C.L.,Deibel Jr., M.R.,Chidester, C.G.,Watenpaugh, K.D.; Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.; J.Mol.Biol., 293:559-568, 1999; PubMed: 10543950; DOI: 10.1006/jmbi.1999.3168

Experimental method