Summary for 1CN4
Entry DOI | 10.2210/pdb1cn4/pdb |
Descriptor | PROTEIN (ERYTHROPOIETIN RECEPTOR), PROTEIN (ERYTHROPOIETIN) (3 entities in total) |
Functional Keywords | hematopoietic cytokine, cytokine receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform EPOR-S: Secreted : P19235 Secreted: P01588 |
Total number of polymer chains | 3 |
Total formula weight | 69011.48 |
Authors | Stroud, R.M.,Reid, S.W. (deposition date: 1999-05-25, release date: 1999-08-11, Last modification date: 2024-10-09) |
Primary citation | Syed, R.S.,Reid, S.W.,Li, C.,Cheetham, J.C.,Aoki, K.H.,Liu, B.,Zhan, H.,Osslund, T.D.,Chirino, A.J.,Zhang, J.,Finer-Moore, J.,Elliott, S.,Sitney, K.,Katz, B.A.,Matthews, D.J.,Wendoloski, J.J.,Egrie, J.,Stroud, R.M. Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature, 395:511-516, 1998 Cited by PubMed: 9774108DOI: 10.1038/26773 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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