1CN4

ERYTHROPOIETIN COMPLEXED WITH EXTRACELLULAR DOMAINS OF ERYTHROPOIETIN RECEPTOR

Replaces:  1BLW

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	PROTEIN (ERYTHROPOIETIN RECEPTOR)	polymer	228	25273.6	2	UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB	Homo sapiens (human)
2	C	PROTEIN (ERYTHROPOIETIN)	polymer	166	18464.3	1	UniProt (P01588) Pfam (PF00758) In PDB	Homo sapiens (human)
3		water	water		18.0	15	Chemie (HOH)

Sequence modifications

A, B: 1 - 225 (UniProt: P19235)

PDB	External Database	Details
Gln 52	Asn 76	engineered mutation
Gln 164	Asn 188	engineered mutation
Glu 211	Ala 235	engineered mutation

C: 1 - 166 (UniProt: P01588)

PDB	External Database	Details
Lys 24	Asn 51	engineered mutation
Lys 38	Asn 65	engineered mutation
Lys 83	Asn 110	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	69011.5
All*	Total formula weight	69011.5

*Water molecules are not included.