1CE1

1.9A STRUCTURE OF THE THERAPEUTIC ANTIBODY CAMPATH-1H FAB IN COMPLEX WITH A SYNTHETIC PEPTIDE ANTIGEN

Summary for 1CE1

DescriptorPROTEIN (CAMPATH-1H:LIGHT CHAIN), PROTEIN (CAMPATH-1H:HEAVY CHAIN), PROTEIN (PEPTIDE ANTIGEN), ... (4 entities in total)
Functional Keywordstherapeutic, antibody, cd52, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total molecular weight47575.07
Authors
James, L.C.,Hale, G.,Waldmann, H.,Bloomer, A.C. (deposition date: 1999-03-12, release date: 1999-06-25, Last modification date: 2013-09-18)
Primary citation
James, L.C.,Hale, G.,Waldmann, H.,Bloomer, A.C.
1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.
J.Mol.Biol., 289:293-301, 1999
PubMed: 10366506 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1999.2750
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers100.2%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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