1CDK

CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (E.C.2.7.1.37) (PROTEIN KINASE A) COMPLEXED WITH PROTEIN KINASE INHIBITOR PEPTIDE FRAGMENT 5-24 (PKI(5-24) ISOELECTRIC VARIANT CA) AND MN2+ ADENYLYL IMIDODIPHOSPHATE (MNAMP-PNP) AT PH 5.6 AND 7C AND 4C

Summary for 1CDK

Entry DOI	10.2210/pdb1cdk/pdb
Descriptor	CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	complex (transferase-inhibitor), transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Sus scrofa (pig) More
Cellular location	Cytoplasm: P00517
Total number of polymer chains	4
Total formula weight	87392.52
Authors	Bossemeyer, D.,Engh, R.A.,Kinzel, V.,Ponstingl, H.,Huber, R. (deposition date: 1994-07-04, release date: 1995-10-15, Last modification date: 2012-07-18)
Primary citation	Bossemeyer, D.,Engh, R.A.,Kinzel, V.,Ponstingl, H.,Huber, R. Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24). EMBO J., 12:849-859, 1993 Cited by PubMed: 8384554 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation