1BTH

STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR

1BTH の概要

• エントリーDOI: 10.2210/pdb1bth/pdb
• 分子名称: THROMBIN, BOVINE PANCREATIC TRYPSIN INHIBITOR, ... (4 entities in total)
• 機能のキーワード: thrombin inhibitor, serine proteinase kunitz-like inhibitor, (serine protease/inhibitor), complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor)
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734; Secreted: P00974
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 80866.73

構造登録者

Van De Locht, A.,Bode, W.,Stubbs, M.T. (登録日: 1996-12-03, 公開日: 1997-12-24, 最終更新日: 2021-11-03)

• 主引用文献: van de Locht, A.,Bode, W.,Huber, R.,Le Bonniec, B.F.,Stone, S.R.,Esmon, C.T.,Stubbs, M.T.; The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin.; EMBO J., 16:2977-2984, 1997; PubMed: 9214615; DOI: 10.1093/emboj/16.11.2977

実験手法

X-RAY DIFFRACTION (2.3 Å)