1BPZ

HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA

Summary for 1BPZ

Related1BPX 1BPY
DescriptorDNA (5'-D(*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*G)-3'), ... (6 entities in total)
Functional Keywordsnucleotidyltransferase, dna repair, base excision repair pathway, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight48042.04
Authors
Sawaya, M.R.,Prasad, R.,Wilson, S.H.,Kraut, J.,Pelletier, H. (deposition date: 1997-04-14, release date: 1997-06-16, Last modification date: 2011-07-13)
Primary citation
Sawaya, M.R.,Prasad, R.,Wilson, S.H.,Kraut, J.,Pelletier, H.
Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism.
Biochemistry, 36:11205-11215, 1997
PubMed: 9287163 (PDB entries with the same primary citation)
DOI: 10.1021/bi9703812
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers847.0%18.2%17.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution