1BKC
CATALYTIC DOMAIN OF TNF-ALPHA CONVERTING ENZYME (TACE)
Summary for 1BKC
Entry DOI | 10.2210/pdb1bkc/pdb |
Related PRD ID | PRD_000919 |
Descriptor | TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME, ZINC ION, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ... (6 entities in total) |
Functional Keywords | zn-endopeptidase, hydrolase, tnf-alpha |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P78536 P78536 P78536 |
Total number of polymer chains | 4 |
Total formula weight | 117771.63 |
Authors | Maskos, K.,Fernandez-Catalan, C.,Bode, W. (deposition date: 1998-04-23, release date: 1999-06-22, Last modification date: 2021-11-03) |
Primary citation | Maskos, K.,Fernandez-Catalan, C.,Huber, R.,Bourenkov, G.P.,Bartunik, H.,Ellestad, G.A.,Reddy, P.,Wolfson, M.F.,Rauch, C.T.,Castner, B.J.,Davis, R.,Clarke, H.R.,Petersen, M.,Fitzner, J.N.,Cerretti, D.P.,March, C.J.,Paxton, R.J.,Black, R.A.,Bode, W. Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme. Proc.Natl.Acad.Sci.USA, 95:3408-3412, 1998 Cited by PubMed: 9520379DOI: 10.1073/pnas.95.7.3408 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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