1BHG

HUMAN BETA-GLUCURONIDASE AT 2.6 A RESOLUTION

Summary for 1BHG

• Entry DOI: 10.2210/pdb1bhg/pdb
• Descriptor: BETA-GLUCURONIDASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: lysosomal enzyme, acid hydrolase, glycosidase
• Biological source: Homo sapiens (human)
• Cellular location: Lysosome: P08236
• Total number of polymer chains: 2
• Total formula weight: 144644.51

Authors

Jain, S.,Drendel, W.B. (deposition date: 1996-03-04, release date: 1997-09-17, Last modification date: 2020-07-29)

• Primary citation: Jain, S.,Drendel, W.B.,Chen, Z.W.,Mathews, F.S.,Sly, W.S.,Grubb, J.H.; Structure of human beta-glucuronidase reveals candidate lysosomal targeting and active-site motifs.; Nat.Struct.Biol., 3:375-381, 1996; PubMed: 8599764; DOI: 10.1038/nsb0496-375

Experimental method

X-RAY DIFFRACTION (2.53 Å)