1AI9
CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE
Summary for 1AI9
Entry DOI | 10.2210/pdb1ai9/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | oxidoreductase, antifungal target, reductase |
Biological source | Candida albicans |
Total number of polymer chains | 2 |
Total formula weight | 45879.90 |
Authors | Whitlow, M.,Howard, A.J.,Stewart, D. (deposition date: 1997-05-01, release date: 1997-11-12, Last modification date: 2024-04-03) |
Primary citation | Whitlow, M.,Howard, A.J.,Stewart, D.,Hardman, K.D.,Kuyper, L.F.,Baccanari, D.P.,Fling, M.E.,Tansik, R.L. X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex. J.Biol.Chem., 272:30289-30298, 1997 Cited by PubMed: 9374515DOI: 10.1074/jbc.272.48.30289 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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