1AI9

CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE

Summary for 1AI9

Entry DOI	10.2210/pdb1ai9/pdb
Descriptor	DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	oxidoreductase, antifungal target, reductase
Biological source	Candida albicans
Total number of polymer chains	2
Total formula weight	45879.90
Authors	Whitlow, M.,Howard, A.J.,Stewart, D. (deposition date: 1997-05-01, release date: 1997-11-12, Last modification date: 2024-04-03)
Primary citation	Whitlow, M.,Howard, A.J.,Stewart, D.,Hardman, K.D.,Kuyper, L.F.,Baccanari, D.P.,Fling, M.E.,Tansik, R.L. X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex. J.Biol.Chem., 272:30289-30298, 1997 Cited by PubMed: 9374515 DOI: 10.1074/jbc.272.48.30289 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation