1AAY

ZIF268 ZINC FINGER-DNA COMPLEX

Summary for 1AAY

• Entry DOI: 10.2210/pdb1aay/pdb
• Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*GP*CP*CP*CP*AP*CP*GP*C)-3'), PROTEIN (ZIF268 ZINC FINGER PEPTIDE), ... (5 entities in total)
• Functional Keywords: zinc finger, dna-binding protein, complex (zinc finger-dna), transcription-dna complex, transcription/dna
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 3
• Total formula weight: 17759.11

Authors

Elrod-Erickson, M.,Rould, M.A.,Pabo, C.O. (deposition date: 1997-01-18, release date: 1997-04-21, Last modification date: 2023-08-02)

Primary citation

Elrod-Erickson, M.,Rould, M.A.,Nekludova, L.,Pabo, C.O.
Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions.
Structure, 4:1171-1180, 1996

PubMed Abstract: Zinc fingers of the Cys2 His2 class recognize a wide variety of different DNA sequences and are one of the most abundant DNA-binding motifs found in eukaryotes. The previously determined 2.1 A structure of a complex containing the three zinc fingers from Zif268 has served as a basis for many modeling and design studies, and Zif268 has proved to be a very useful model system for studying how TFIIIA-like zinc fingers recognize DNA.

PubMed: 8939742
DOI: 10.1016/S0969-2126(96)00125-6

Experimental method

X-RAY DIFFRACTION (1.6 Å)