1A2E

CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA DECAMER CONTAINING A CISPLATIN INTERSTRAND CROSS-LINK ADDUCT

Summary for 1A2E

• Entry DOI: 10.2210/pdb1a2e/pdb
• Descriptor: DNA (5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3'), Cisplatin, ... (4 entities in total)
• Functional Keywords: antitumor drug, cis-ddp, interstrand cross-link, dna
• Total number of polymer chains: 2
• Total formula weight: 6391.04

Authors

Coste, F.,Zelwer, C. (deposition date: 1998-01-05, release date: 1999-04-12, Last modification date: 2024-02-07)

• Primary citation: Coste, F.,Malinge, J.M.,Serre, L.,Shepard, W.,Roth, M.,Leng, M.,Zelwer, C.; Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated site.; Nucleic Acids Res., 27:1837-1846, 1999; PubMed: 10101191; DOI: 10.1093/nar/27.8.1837

Experimental method

X-RAY DIFFRACTION (1.63 Å)