1ZS5

Structure-based evaluation of selective and non-selective small molecules that block HIV-1 TAT and PCAF association

Summary for 1ZS5

• Entry DOI: 10.2210/pdb1zs5/pdb
• Related: 1WUG 1WUM
• NMR Information: BMRB: 6507,6508
• Descriptor: Histone acetyltransferase PCAF, (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE (2 entities in total)
• Functional Keywords: bromodomain, histone-acetyltransferase, nmr-structure chemical ligand, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (By similarity): Q92831
• Total number of polymer chains: 1
• Total formula weight: 14251.47

Authors

Zeng, L.,Godbole, S.,Muller, M.,Yan, S.,Sanchez, R.,Zhou, M. (deposition date: 2005-05-23, release date: 2006-05-23, Last modification date: 2024-05-22)

• Primary citation: Zeng, L.,Godbole, S.,Muller, M.,Yan, S.,Sanchez, R.,Zhou, M.; Structure-based evaluation of selective nad non-selective small molecules that block hiv-1 tat and pcaf association; TO BE PUBLISHED,

Experimental method

SOLUTION NMR