1ZNV

How a His-metal finger endonuclease ColE7 binds and cleaves DNA with a transition metal ion cofactor

Summary for 1ZNV

Entry DOI	10.2210/pdb1znv/pdb
Related	1M08 1MZ8 1PT3 7CEI
Descriptor	Colicin E7 immunity protein, Colicin E7, NICKEL (II) ION, ... (5 entities in total)
Functional Keywords	h-n-h motif, ni-binding, protein-protein complex, endonuclease, hydrolase-protein binding complex, hydrolase/protein binding
Biological source	Escherichia coli str. K12 substr. More
Total number of polymer chains	4
Total formula weight	52579.93
Authors	Doudeva, L.G.,Huang, H.,Hsia, K.C.,Shi, Z.,Li, C.L.,Shen, Y.,Yuan, H.S. (deposition date: 2005-05-12, release date: 2006-03-14, Last modification date: 2023-10-25)
Primary citation	Doudeva, L.G.,Huang, H.,Hsia, K.C.,Shi, Z.,Li, C.L.,Shen, Y.,Cheng, Y.S.,Yuan, H.S. Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+ Protein Sci., 15:269-280, 2006 Cited by PubMed: 16434744 DOI: 10.1110/ps.051903406 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation