1Z7G

Free human HGPRT

Summary for 1Z7G

Entry DOI	10.2210/pdb1z7g/pdb
Related	1BZY 1D6N 1HMP
Descriptor	Hypoxanthine-guanine phosphoribosyltransferase (2 entities in total)
Functional Keywords	flexibility, trans cis peptide bond isomerization, nucleotide binding, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00492
Total number of polymer chains	4
Total formula weight	97924.87
Authors	Keough, D.T.,Brereton, I.M.,de Jersey, J.,Guddat, L.W. (deposition date: 2005-03-24, release date: 2005-08-02, Last modification date: 2023-08-23)
Primary citation	Keough, D.T.,Brereton, I.M.,de Jersey, J.,Guddat, L.W. The Crystal Structure of Free Human Hypoxanthine-guanine Phosphoribosyltransferase Reveals Extensive Conformational Plasticity Throughout the Catalytic Cycle J.Mol.Biol., 351:170-181, 2005 Cited by PubMed: 15990111 DOI: 10.1016/j.jmb.2005.05.061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation