1XMJ
Crystal structure of human deltaF508 human NBD1 domain with ATP
Summary for 1XMJ
Entry DOI | 10.2210/pdb1xmj/pdb |
Related | 1Q3H 1R0W 1R0X 1R0Y 1R0Z 1R10 1XMI |
Descriptor | Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | cftr; nbd1 domain; deltaf508; cystic fibrosis; nucleotide-binding domain 1, membrane protein, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 32885.25 |
Authors | Lewis, H.A.,Zhao, X.,Wang, C.,Sauder, J.M.,Rooney, I.,Noland, B.W.,Lorimer, D.,Kearins, M.C.,Conners, K.,Condon, B.,Maloney, P.C.,Guggino, W.B.,Hunt, J.F.,Emtage, S.,Structural GenomiX (deposition date: 2004-10-02, release date: 2004-11-09, Last modification date: 2024-04-03) |
Primary citation | Lewis, H.A.,Zhao, X.,Wang, C.,Sauder, J.M.,Rooney, I.,Noland, B.W.,Lorimer, D.,Kearins, M.C.,Conners, K.,Condon, B.,Maloney, P.C.,Guggino, W.B.,Hunt, J.F.,Emtage, S. Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure J.Biol.Chem., 280:1346-1353, 2005 Cited by PubMed: 15528182DOI: 10.1074/jbc.M410968200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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