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1XMI

Crystal structure of human F508A NBD1 domain with ATP

Summary for 1XMI
Entry DOI10.2210/pdb1xmi/pdb
Related1Q3H 1R0W 1R0X 1R0Y 1R0Z 1R10 1XMJ
DescriptorCystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywordscftr; nbd1 domain; f508a; cystic fibrosis; nucleotide-binding domain 1, membrane protein, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains5
Total formula weight165046.88
Authors
Primary citationLewis, H.A.,Zhao, X.,Wang, C.,Sauder, J.M.,Rooney, I.,Noland, B.W.,Lorimer, D.,Kearins, M.C.,Conners, K.,Condon, B.,Maloney, P.C.,Guggino, W.B.,Hunt, J.F.,Emtage, S.
Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure
J.Biol.Chem., 280:1346-1353, 2005
Cited by
PubMed: 15528182
DOI: 10.1074/jbc.M410968200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

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