1XFP
Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme
Summary for 1XFP
Entry DOI | 10.2210/pdb1xfp/pdb |
Related | 1JTT |
Descriptor | heavy chain antibody, Lysozyme C, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | beta sandwich, immunoglobulin fold, protein-protein heterocomplex, alpha-beta othogonal bundle, immune system-hydrolase complex, immune system/hydrolase |
Biological source | Camelus dromedarius (Arabian camel) More |
Cellular location | Secreted: P00698 |
Total number of polymer chains | 2 |
Total formula weight | 29829.81 |
Authors | De Genst, E.,Handelberg, F.,Van Meirhaeghe, A.,Vynck, S.,Loris, R.,Wyns, L.,Muyldermans, S. (deposition date: 2004-09-15, release date: 2004-09-28, Last modification date: 2013-02-06) |
Primary citation | De Genst, E.,Handelberg, F.,Van Meirhaeghe, A.,Vynck, S.,Loris, R.,Wyns, L.,Muyldermans, S. Chemical Basis for the Affinity Maturation of a Camel Single Domain Antibody J.Biol.Chem., 279:53593-53601, 2004 Cited by PubMed: 15383540DOI: 10.1074/jbc.M407843200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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