1XD2

Crystal Structure of a ternary Ras:SOS:Ras*GDP complex

Summary for 1XD2

Entry DOI	10.2210/pdb1xd2/pdb
Related	1BKD 1NVU 1NVV 1NVW 1NVX 1XD4
Descriptor	Transforming protein p21/H-Ras-1, Son of sevenless protein homolog 1, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	ras:sos complex, ras-nucleotide exchange factor complex, signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 P01112
Total number of polymer chains	3
Total formula weight	95293.68
Authors	Sondermann, H.,Soisson, S.M.,Boykevisch, S.,Yang, S.S.,Bar-Sagi, D.,Kuriyan, J. (deposition date: 2004-09-03, release date: 2004-11-02, Last modification date: 2023-08-23)
Primary citation	Sondermann, H.,Soisson, S.M.,Boykevisch, S.,Yang, S.S.,Bar-Sagi, D.,Kuriyan, J. Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119:393-405, 2004 Cited by PubMed: 15507210 DOI: 10.1016/j.cell.2004.10.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation