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1XD2

Crystal Structure of a ternary Ras:SOS:Ras*GDP complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transforming protein p21/H-Ras-1polymer16618783.11UniProt (P01112)
Pfam (PF00071)
Homo sapiens (human)c-H-ras
2B
(B)
Transforming protein p21/H-Ras-1polymer16618875.21UniProt (P01112)
Pfam (PF00071)
Homo sapiens (human)c-H-ras
3C
(C)
Son of sevenless protein homolog 1polymer48456788.01UniProt (Q07889)
Pfam (PF00618)
Pfam (PF00617)
Homo sapiens (human)SOS-1
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
5E, G, H, I
(A, B, C)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
PubChem (1061)
6F
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
Sequence modifications
A: 1 - 166 (UniProt: P01112)
PDBExternal DatabaseDetails
Ala 64Tyr 64engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight94446.3
Non-Polymers*Number of molecules6
Total formula weight847.4
All*Total formula weight95293.7
*Water molecules are not included.

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PDB entries from 2026-04-01

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