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1XD2

Crystal Structure of a ternary Ras:SOS:Ras*GDP complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transforming protein p21/H-Ras-1polymer16618783.11UniProt (P01112)
Pfam (PF00071)
Homo sapiens (human)c-H-ras
2B
(B)
Transforming protein p21/H-Ras-1polymer16618875.21UniProt (P01112)
Pfam (PF00071)
Homo sapiens (human)c-H-ras
3C
(C)
Son of sevenless protein homolog 1polymer48456788.01UniProt (Q07889)
Pfam (PF00618)
Pfam (PF00617)
Homo sapiens (human)SOS-1
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E, G, H, I
(A, B, C)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
6F
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
Sequence modifications
A: 1 - 166 (UniProt: P01112)
PDBExternal DatabaseDetails
Ala 64Tyr 64engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight94446.3
Non-Polymers*Number of molecules6
Total formula weight847.4
All*Total formula weight95293.7
*Water molecules are not included.

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