1NVX
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Summary for 1NVX
Entry DOI | 10.2210/pdb1nvx/pdb |
Related | 1BKD 1NVU 1NVV 1NVW |
Descriptor | Transforming protein p21/H-RAS-1, Son of sevenless protein homolog 1, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | proto-oncogene, gtp-binding, guanine-nucleotide releasing factor, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 |
Total number of polymer chains | 3 |
Total formula weight | 94897.52 |
Authors | Margarit, S.M.,Sondermann, H.,Hall, B.E.,Nagar, B.,Hoelz, A.,Pirruccello, M.,Bar-Sagi, D.,Kuriyan, J. (deposition date: 2003-02-04, release date: 2003-04-01, Last modification date: 2023-08-16) |
Primary citation | Margarit, S.M.,Sondermann, H.,Hall, B.E.,Nagar, B.,Hoelz, A.,Pirruccello, M.,Bar-Sagi, D.,Kuriyan, J. Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS Cell(Cambridge,Mass.), 112:685-695, 2003 Cited by PubMed: 12628188DOI: 10.1016/S0092-8674(03)00149-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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