1WVJ

Exploring the GluR2 ligand-binding core in complex with the bicyclic AMPA analogue (S)-4-AHCP

Summary for 1WVJ

Entry DOI	10.2210/pdb1wvj/pdb
Related	1FTJ 1FTM 1M5B
Descriptor	ionotropic glutamate receptor 2, SULFATE ION, 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE, ... (5 entities in total)
Functional Keywords	ionotropic glutamate receptor glur2, ligand-binding core, complex with bicyclic ampa analogue, membrane protein
Biological source	Rattus norvegicus (Norway rat) More
Cellular location	Cell membrane; Multi-pass membrane protein: P19491
Total number of polymer chains	1
Total formula weight	29928.33
Authors	Nielsen, B.B.,Pickering, D.S.,Greenwood, J.R.,Brehm, L.,Gajhede, M.,Schousboe, A.,Kastrup, J.S. (deposition date: 2004-12-15, release date: 2005-04-26, Last modification date: 2023-10-25)
Primary citation	Nielsen, B.B.,Pickering, D.S.,Greenwood, J.R.,Brehm, L.,Gajhede, M.,Schousboe, A.,Kastrup, J.S. Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP FEBS J., 272:1639-1648, 2005 Cited by PubMed: 15794751 DOI: 10.1111/j.1742-4658.2005.04583.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation