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1WVJ

Exploring the GluR2 ligand-binding core in complex with the bicyclic AMPA analogue (S)-4-AHCP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1Aionotropic glutamate receptor 2polymer26329221.71UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
In PDB
Rattus norvegicus (Norway rat)Glutamate receptor 2
2ASULFATE IONnon-polymer96.12Chemie (SO4)
3A3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINEnon-polymer238.21Chemie (IBC)
4AGLYCEROLnon-polymer92.13Chemie (GOL)
5waterwater18.0309Chemie (HOH)
Sequence modifications
A: 3 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 1-cloning artifact
Ala 2-cloning artifact
A: 120 - 263 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29221.7
Non-Polymers*Number of molecules6
Total formula weight706.6
All*Total formula weight29928.3
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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