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1WSG

Co-crystal structure of E.coli RNase HI active site mutant (E48A/D134N*) with Mn2+

Summary for 1WSG
Entry DOI10.2210/pdb1wsg/pdb
Related1WSE 1WSF 1WSH 1WSI 1WSJ
DescriptorRibonuclease HI, MANGANESE (II) ION (3 entities in total)
Functional Keywordsrnase h, active-site mutant, co-crystal structure with mn2+, metal fluctuation model, hydrolase
Biological sourceEscherichia coli
Cellular locationCytoplasm (Potential): P0A7Y4
Total number of polymer chains4
Total formula weight70133.37
Authors
Tsunaka, Y.,Takano, K.,Matsumura, H.,Yamagata, Y.,Kanaya, S. (deposition date: 2004-11-05, release date: 2005-02-08, Last modification date: 2021-11-10)
Primary citationTsunaka, Y.,Takano, K.,Matsumura, H.,Yamagata, Y.,Kanaya, S.
Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345:1171-1183, 2005
Cited by
PubMed: 15644213
DOI: 10.1016/j.jmb.2004.11.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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