1W80

Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170

Summary for 1W80

• Entry DOI: 10.2210/pdb1w80/pdb
• Related: 1B9K 1GW5 1KY6 1KY7 1KYD 1KYF 1KYU 1QTP 1QTS
• Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 2 ALPHA 2 SUBUNIT, SYNAPTOJANIN 1, BENZAMIDINE, ... (8 entities in total)
• Functional Keywords: endocytosis/exocytosis, endocytosis, alpha-adaptin appendage, adaptor complex, ap2, synaptojanin, exocytosis, lipid-binding, endocytosis-exocytosis complex
• Biological source: MUS MUSCULUS (MOUSE); More
• Cellular location: Cell membrane: P17427; Cytoplasm (By similarity): O43426 O43426
• Total number of polymer chains: 3
• Total formula weight: 31404.42

Authors

Ford, M.G.J.,Praefcke, G.J.K.,McMahon, H.T. (deposition date: 2004-09-14, release date: 2004-10-27, Last modification date: 2023-12-13)

• Primary citation: Praefcke, G.J.K.,Ford, M.G.J.,Schmid, E.M.,Olesen, L.E.,Gallop, J.L.,Peak-Chew, S.-Y.,Vallis, Y.,Babu, M.M.,Mills, I.G.,Mcmahon, H.T.; Evolving Nature of the Ap2 Alpha-Appendage Hub During Clathrin-Coated Vesicle Endocytosis.; Embo J., 23:4371-, 2004; PubMed: 15496985; DOI: 10.1038/SJ.EMBOJ.7600445

Experimental method

X-RAY DIFFRACTION (1.9 Å)