1W80
Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADAPTER-RELATED PROTEIN COMPLEX 2 ALPHA 2 SUBUNIT | polymer | 250 | 28048.0 | 1 | UniProt (P17427) Pfam (PF02883) Pfam (PF02296) | MUS MUSCULUS (MOUSE) | ALPHA-ADAPTIN C, ADAPTOR PROTEIN COMPLEX AP-2 ALPHA-2 SUBUNIT, CLATHRIN ASSEMBLY, PROTEIN COMPLEX 2 ALPHA-C LARGE CHAIN, 100 KDA COATED VESICLE PROTEIN, PLASMA MEMBRANE ADAPTOR HA2/AP2 ADAPTIN ALPHA C SUBUNIT, ALPHA-ADAPTIN APPENDAGE DOMAIN FROM AP2 |
| 2 | B (P) | SYNAPTOJANIN 1 | polymer | 12 | 1465.5 | 1 | UniProt (O43426) | HOMO SAPIENS | SYNAPTIC INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE 1, SYJ-P3 |
| 3 | C (Q) | SYNAPTOJANIN 1 | polymer | 12 | 1342.4 | 1 | UniProt (O43426) | HOMO SAPIENS | SYNAPTIC INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE 1, SYJ-P3 |
| 4 | D (A) | BENZAMIDINE | non-polymer | 120.2 | 1 | Chemie (BEN) | |||
| 5 | E, F, G (A) | CARBONATE ION | non-polymer | 60.0 | 3 | Chemie (CO3) | |||
| 6 | H (A) | DITHIANE DIOL | non-polymer | 152.2 | 1 | Chemie (DTD) | |||
| 7 | I (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | J, K, L (A, P, Q) | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
A: 689 - 694 (PDB: 1W80)
A: 695 - 938 (UniProt: P17427)
| PDB | External Database | Details |
|---|---|---|
| Gly 889 | Val 889 | conflict |
| Ala 890 | Leu 889 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 30855.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 548.5 | |
| All* | Total formula weight | 31404.4 |
